Endocrine Abstracts

There are increasing evidences that leptin, a protein secreted by adipose tissue, may be an important factor contributing to the development of atherosclerosis. In this study, the relationship between plasma leptin levels and markers of inflammation and endothelial activation was investigated in 214 obese nondiabetic children and adolescents. Fasting levels of leptin, C-reactive protein (CRP), fibrinogen (FB), interleukin-6 (IL-6), interleukin-1β (IL-1β), intercellul...

Objectives: GH plays a crucial role in the regulation of metabolism of human cells. Nevertheless, a direct influence of this hormone on the proliferation, maturation and differentiation of human early hematopoietic stem/progenitor cells (HSPCs) has not been investigated thoroughly. Moreover, certain deviations of hematological parameters, such as anemia or leucopenia, are commonly observed in patients with growth hormone deficiency (GHD) syndrome, which might be substantially ...